Microdosing

What microdosing is

Repeatedly taking a small amount of a psychedelic, usually psilocybin or LSD, meant to stay sub-intoxicating: below the level where the effects impact your daily function.^1,2

Researchers haven't agreed on how small, or how often.¹ Studies generally describe low doses taken on some days and not others, over a period of weeks.^2,3

This guide gives no amounts or schedules. The work offered on this site doesn't include dosing guidance.

Safety

Medications

Reports link lithium taken with a psychedelic to seizures. In one analysis of 62 such reports, 47% described a seizure.⁸

People taking common antidepressants, SSRIs and SNRIs, often report weaker psychedelic effects.^9,10 One controlled study found escitalopram, an SSRI, left psilocybin's positive effects on mood in place.¹¹

Questions about a prescription belong with whoever prescribed it.

Who research screens out

Research safety guidelines exclude people with a personal or family history of psychosis or bipolar disorder, and people who are pregnant. Because psychedelics raise pulse and blood pressure, the same guidelines check the heart first.¹² Data on use during pregnancy are very limited.¹³

Those guidelines were written for research at full doses.¹² Return to Baseline has its own screening, which its application sets out before asking anything.

How the work here fits

The work offered here is education, preparation and integration support around a protocol someone has already decided to run.

It doesn't include supplying, recommending or dosing any substance, or being present for anything illegal where it happens.

Most of the attention goes to the practices around a protocol: breath, movement and attention, done daily and tracked. They keep going after the protocol ends.